Chloramphenicol


What is Chloramphenicol for ?

This medication is an antibiotic, prescribed for certain types of bacterial infection. It kills or slows the growth of sensitive bacteria.

How does Chloramphenicol work ?

Chloramphenicol works to harm the bacteria and fight the infection.

How should Chloramphenicol be used ?

Adult: PO- The recommended dose is 50 mgkgday in 4 divided doses, may increase to 100 mgkgday in more severe infections. Eye Drops: As 0.5% solution: Instill 1 or 2 drops 2 hourly. It comes as a tablet to take by mouth, on an empty stomach. It also comes as eye drops to instill into the affected eyes as directed by your physician.

Common side effects of Chloramphenicol ?

Bad taste in your mouth. This most often goes back to normal. Upset stomach or throwing up. Many small meals, good mouth care, sucking hard, sugar-free candy, or chewing sugar-free gum may help. Loose stools (diarrhea). Yogurt or probiotics may help. You may get these products at health food stores or in some pharmacies. Anemia, low white blood cell count, and low platelet count may rarely happen. Feeling dizzy. Rise slowly over a few minutes when sitting or lying down. Be careful climbing. For women, vaginal yeast infection. Report itching or discharge. A small number of people may have low blood pressure or more acid in the blood.

What do I do if I miss a dose ?

Call your doctor to find out what to do.

What precautions should I take when taking Chloramphenicol ?

If you have an allergy to chloramphenicol or any other part of this drug. - Tell your doctor if you are allergic to any drugs. Make sure to tell about the allergy and what signs you had. This includes telling about rash; hives; itching; shortness of breath; wheezing; cough; swelling of face, lips, tongue, or throat; or any other signs. - If you have any of these health problems: Bone marrow disease, liver disease, low blood cell count, or poor kidney function. - If you have G6PD deficiency.

When do I need to seek medical help ?

If you think there was an overdose, call your local poison control center or ER right away. Signs of a very bad reaction to the drug. These include wheezing; chest tightness; fever; itching; bad cough; blue or gray skin color; seizures; or swelling of face, lips, tongue, or throat. Very bad dizziness or passing out. Very upset stomach or throwing up. Feeling very tired or weak. Very loose stools (diarrhea), even after drug is stopped. Any bruising or bleeding. Any rash. Side effect or health problem is not better or you are feeling worse.

Can I take Chloramphenicol with other medicines ?

Sometimes drugs are not safe when you take them with certain other drugs and food. - Taking them together can cause bad side effects. - Be sure to talk to your doctor about all the drugs you take.

Are there any food restrictions ?

Avoid alcohol.

How do I store Chloramphenicol ?

Store it at controlled room temperature (15-30oC).

Pregnancy Category ?

Category C : Animal reproduction studies have shown an adverse effect on the fetus and there are no adequate and well-controlled studies in humans, but potential benefits may warrant use of the drug in pregnant women despite potential risks.

Therapeutic Classification ?

Chloramphenicols , Eye Anti-Infectives & Antiseptics , Ear Anti-Infectives & Antiseptics.