Clopidogrel


What is Clopidogrel for ?

This medication is an anti-platelet agent, that is, a drug that inhibits the ability of platelets to clump together as part of a blood clot. This medication is prescribed either alone or with other medications for prevention or treatment of stroke and heart attack (which are usually caused by blood clots) in persons who are at high risk.

How does Clopidogrel work ?

Clopidogrel stops platelets from getting sticky and clumping.

How should Clopidogrel be used ?

Oral- Prophylaxis of blood clot events- 75 mg once daily. Acute coronary syndrome For ST-elevation myocardial infarction: with aspirin: 75 mg once daily. For unstable angina, non-ST-elevation myocardial infarction: Initial: 300 mg loading dose, followed by 75 mg once daily (with aspirin 75-325 mg once daily). It comes as a tablet to take by mouth. It is usually taken once a day with or without food.

Common side effects of Clopidogrel ?

Itching. Bleeding. Bruising. Nosebleed.

What do I do if I miss a dose ?

Take a missed dose as soon as you think about it. - If it is close to the time for your next dose, skip the missed dose and go back to your normal time. - Do not take 2 doses at the same time or extra doses. - Do not change the dose or stop this drug. - Talk with the doctor.

What precautions should I take when taking Clopidogrel ?

Alert your doctor immediately if you have a history of any of these conditions: - bleeding disorders, for example, haemophilia. - stomach ulcers, especially if you have ever bled from a stomach ulcer. - low blood cell count (platelets, red or white blood cells). - liver disease. Clopidogrel may increase the risk of abnormal bleeding. It is important to alert your doctor if you have any of these illnesses, as the risk of bleeding may be further increased.

When do I need to seek medical help ?

If you think there was an overdose, call your local poison control center or ER right away. Signs of a very bad reaction to the drug. These include wheezing; chest tightness; fever; itching; bad cough; blue or gray skin color; seizures; or swelling of face, lips, tongue, or throat. Chest pain or pressure. Change in strength on 1 side is greater than the other, trouble speaking or thinking, change in balance, or blurred eyesight. Trouble breathing. Feeling very tired or weak. Change in thinking clearly and with logic. Sudden change in eyesight. Any bruising or bleeding. Yellow skin or eyes. Change in skin color to black or purple. Any rash. Side effect or health problem is not better or you are feeling worse.

Can I take Clopidogrel with other medicines ?

Inform your doctor if you are taking any other medicines, especially these listed here: - other blood-thinning medicines such as warfarin, aspirin and ticlopidine. - painkillers known as NSAIDs, for example, diclofenac, ibuprofen, naproxen, mefenamic acid. - Avoid medicines such as omeprazole, esomeprazole, cimetidine, fluconazole, ketoconazole, voriconazole, etravirine, felbamate and fluvoxamine. Alert your doctor if you are taking any of these medicines. Do not take antacids together with Clopidogrel. If you must take antacids, take them at least 1 hour before or 2 hours after you have taken Clopidogrel. Antacids can reduce the effectiveness of Clopidogrel when taken together. Always inform your doctor and pharmacist if you are taking any other medicines, including herbal tonics, supplements and medicines that you buy without a prescription.

Are there any food restrictions ?

Avoid Alcohol.

How do I store Clopidogrel ?

Store at 25 °C. Store it in an airtight container and keep away from children.

Pregnancy Category ?

Category B : Animal reproduction studies have failed to demonstrate a risk to the fetus and there are no adequate and well-controlled studies in pregnant women OR Animal studies have shown an adverse effect, but adequate and well-controlled studies in pregnant women have failed to demonstrate a risk to the fetus in any trimester.

Therapeutic Classification ?

Anticoagulants and Antiplatelets.