Co-trimoxazole


What is Co-trimoxazole for ?

This medication is a combination of trimethoprim and sulfamethoxazole, prescribed for certain types bacterial infections. It is also used to treat traveler’s diarrhea. It eliminates bacteria that cause various infections.

How should Co-trimoxazole be used ?

It is a fixed combination product containing sulfamethoxazole and trimethoprim in 5:1 ratio. Adult- PO- The recommended dose is 2 tablets every 12 hours for a period of 10 to 14 days. Child- The recommended dose is 8 mg/kg of trimethoprim and 40 mg/kg of sulfamethoxazole daily in 2 divided doses every 12 hours.

Common side effects of Co-trimoxazole ?

Nausea, vomiting and loss of appetite. Weakness, fatigue and sleeplessness.

What do I do if I miss a dose ?

Many times this drug is taken on an as needed basis.

What precautions should I take when taking Co-trimoxazole ?

Caution should be exercised in patients with history of liver or kidney disease, asthma, severe allergies, glucose-6-phosphate dehydrogenase (G-6-PD) deficiency (an inherited blood disease), any allergy, who are taking other medications. Avoid exposure to sunlight.

Can I take Co-trimoxazole with other medicines ?

It comes as a tablet and liquid to take by mouth, with or without food.

Are there any food restrictions ?

Avoid Alcohol.

How do I store Co-trimoxazole ?

Store it at controlled room temperature (15–25°C), protect from light.

Pregnancy Category ?

Category C : Animal reproduction studies have shown an adverse effect on the fetus and there are no adequate and well-controlled studies in humans, but potential benefits may warrant use of the drug in pregnant women despite potential risks.

Therapeutic Classification ?

Anti- Infectives.