Cycloserine


What is Cycloserine for ?

This medication is an antibiotic, prescribed for tuberculosis (TB). It is also used to treat certain urinary tract infections. It stops or slows the growth of bacterial cells.

How does Cycloserine work ?

Cycloserine works to harm the bacteria and fight the infection.

How should Cycloserine be used ?

PO- With other drugs: Initial: 250 mg twice daily for 2 wk, increase to 0.5-1 gmday in divided doses. Max: 1 gmday. It comes as a tablet or capsule to take by mouth, with or without food.

Common side effects of Cycloserine ?

Feeling lightheaded, sleepy, having blurred eyesight, or a change in thinking clearly. Avoid driving and doing other tasks or actions that call for you to be alert or have clear eyesight until you see how this drug affects you. Headache.

What do I do if I miss a dose ?

Take a missed dose as soon as you think about it. If it is close to the time for your next dose, skip the missed dose and go back to your normal time. Do not take 2 doses at the same time or extra doses. Do not change the dose or stop this drug. Talk with the doctor.

What precautions should I take when taking Cycloserine ?

Do not take this medicine if you ever had an allergic reaction (breathlessness, rashes, swollen eyes) to Cycloserine. - Alert your doctor if you have epilepsy (fits or seizures), depression, severe anxiety, psychosis or other psychiatric conditions. - Alert your doctor if you tend to drink too much alcohol.

When do I need to seek medical help ?

If you think there was an overdose, call your local poison control center or ER right away. Signs of a very bad reaction to the drug. These include wheezing; chest tightness; fever; itching; bad cough; blue or gray skin color; seizures; or swelling of face, lips, tongue, or throat. Signs of low mood (depression), thoughts of killing yourself, nervousness, emotional ups and downs, thinking that is not normal, anxiety, or lack of interest in life. Very bad headache. Very loose stools (diarrhea), even after drug is stopped. Numbness or tingling in your hands or feet. Any rash. Side effect or health problem is not better or you are feeling worse.

Can I take Cycloserine with other medicines ?

Alert your doctor if you are taking any other medicines, especially those listed here: - phenytoin (an epilepsy medicine). - other TB medicines, especially ethionamide and isoniazid When Cycloserine is given together with ethionamide or isoniazid, you may be more likely to experience certain side effects such as drowsiness or dizziness. Watch out for these side effects. If you feel dizzy or drowsy, do not drive or take part in any activity in which you need to be alert. Inform your doctor if these side effects get worse or make you uncomfortable. Always inform your doctor and pharmacist if you are taking any other medicines, including herbal medicines and medicines that you buy without a prescription.

Are there any food restrictions ?

Avoid alcohol. You are more likely to experience serious side effects such as seizures (fits) if you consume alcohol while being treated with Cycloserine. - Eat more of foods that are rich in vitamin B12 and folate (folic acid). Sources of folate include cereals, leafy vegetables (spinach, broccoli, lettuce), bananas, melons, legumes, mushrooms, organ meat (liver, kidney), oranges and tomato juice. Sources of vitamin B12 include fish, shellfish, meat, and dairy products.

How do I store Cycloserine ?

Store it at room temperature.

Pregnancy Category ?

Category C : Animal reproduction studies have shown an adverse effect on the fetus and there are no adequate and well-controlled studies in humans, but potential benefits may warrant use of the drug in pregnant women despite potential risks.

Therapeutic Classification ?

Anti-TB Agents.